48 compound library Search Results


global methylation inhibitor  (TargetMol)
93
TargetMol global methylation inhibitor
The protein expression of MEF2C is regulated by m6A modification. (A,B) MEF2C and FTO protein levels after FTO knockdown and overexpression on the 4th day after differentiation. (C,D) MEF2C and METTL3 protein levels after METTL3 knockdown and overexpression for 4th day post differentiation. (E,F) Treatment with a global <t>methylation</t> inhibitor, 3-Deazaadenosine (DAA), for 24 and 48 h led to the downregulation of the MEF2C protein levels in bovine skeletal myoblasts. The results are presented as the means ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001, siNC vs. siRNA samples and DMSO vs. DAA at 24h; # p < 0.05, # # # p < 0.001, empty vector vs. overexpression plasmid samples and DMSO vs. DAA at 48h), using Student's t test.
Global Methylation Inhibitor, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/global methylation inhibitor/product/TargetMol
Average 93 stars, based on 1 article reviews
global methylation inhibitor - by Bioz Stars, 2026-03
93/100 stars
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48 compound library  (TargetMol)
93
TargetMol 48 compound library
The protein expression of MEF2C is regulated by m6A modification. (A,B) MEF2C and FTO protein levels after FTO knockdown and overexpression on the 4th day after differentiation. (C,D) MEF2C and METTL3 protein levels after METTL3 knockdown and overexpression for 4th day post differentiation. (E,F) Treatment with a global <t>methylation</t> inhibitor, 3-Deazaadenosine (DAA), for 24 and 48 h led to the downregulation of the MEF2C protein levels in bovine skeletal myoblasts. The results are presented as the means ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001, siNC vs. siRNA samples and DMSO vs. DAA at 24h; # p < 0.05, # # # p < 0.001, empty vector vs. overexpression plasmid samples and DMSO vs. DAA at 48h), using Student's t test.
48 Compound Library, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/48 compound library/product/TargetMol
Average 93 stars, based on 1 article reviews
48 compound library - by Bioz Stars, 2026-03
93/100 stars
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diversettm database  (Chembridge)
90
Chembridge diversettm database
The protein expression of MEF2C is regulated by m6A modification. (A,B) MEF2C and FTO protein levels after FTO knockdown and overexpression on the 4th day after differentiation. (C,D) MEF2C and METTL3 protein levels after METTL3 knockdown and overexpression for 4th day post differentiation. (E,F) Treatment with a global <t>methylation</t> inhibitor, 3-Deazaadenosine (DAA), for 24 and 48 h led to the downregulation of the MEF2C protein levels in bovine skeletal myoblasts. The results are presented as the means ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001, siNC vs. siRNA samples and DMSO vs. DAA at 24h; # p < 0.05, # # # p < 0.001, empty vector vs. overexpression plasmid samples and DMSO vs. DAA at 48h), using Student's t test.
Diversettm Database, supplied by Chembridge, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/diversettm database/product/Chembridge
Average 90 stars, based on 1 article reviews
diversettm database - by Bioz Stars, 2026-03
90/100 stars
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chemdiv divsets  (Chemdiv Inc)
90
Chemdiv Inc chemdiv divsets
The protein expression of MEF2C is regulated by m6A modification. (A,B) MEF2C and FTO protein levels after FTO knockdown and overexpression on the 4th day after differentiation. (C,D) MEF2C and METTL3 protein levels after METTL3 knockdown and overexpression for 4th day post differentiation. (E,F) Treatment with a global <t>methylation</t> inhibitor, 3-Deazaadenosine (DAA), for 24 and 48 h led to the downregulation of the MEF2C protein levels in bovine skeletal myoblasts. The results are presented as the means ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001, siNC vs. siRNA samples and DMSO vs. DAA at 24h; # p < 0.05, # # # p < 0.001, empty vector vs. overexpression plasmid samples and DMSO vs. DAA at 48h), using Student's t test.
Chemdiv Divsets, supplied by Chemdiv Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chemdiv divsets/product/Chemdiv Inc
Average 90 stars, based on 1 article reviews
chemdiv divsets - by Bioz Stars, 2026-03
90/100 stars
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molport hts library  (MolPort Inc)
90
MolPort Inc molport hts library
The protein expression of MEF2C is regulated by m6A modification. (A,B) MEF2C and FTO protein levels after FTO knockdown and overexpression on the 4th day after differentiation. (C,D) MEF2C and METTL3 protein levels after METTL3 knockdown and overexpression for 4th day post differentiation. (E,F) Treatment with a global <t>methylation</t> inhibitor, 3-Deazaadenosine (DAA), for 24 and 48 h led to the downregulation of the MEF2C protein levels in bovine skeletal myoblasts. The results are presented as the means ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001, siNC vs. siRNA samples and DMSO vs. DAA at 24h; # p < 0.05, # # # p < 0.001, empty vector vs. overexpression plasmid samples and DMSO vs. DAA at 48h), using Student's t test.
Molport Hts Library, supplied by MolPort Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/molport hts library/product/MolPort Inc
Average 90 stars, based on 1 article reviews
molport hts library - by Bioz Stars, 2026-03
90/100 stars
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en 1948 4 marker pcb calibration series  (Cambridge Isotope Laboratories)
N/A
EN 1948 4 Marker PCB Calibration Series CS2
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en 1948 4 who pcb calibration series  (Cambridge Isotope Laboratories)
N/A
EN 1948 4 WHO PCB Calibration Series CS2
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hrms rapid pcb screening calibration soln cs 0 05  (Cambridge Isotope Laboratories)
N/A
HRMS rapid PCB screening calibration soln CS 0 05 unlabeled 13C12 99
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hrmsrapid pcb screening calibration soln cs 0 5  (Cambridge Isotope Laboratories)
N/A
HRMSrapid PCB screening calibration soln CS 0 5 unlabeled 13C12 99
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hrms rapid pcb screening calibration soln cs 0 1  (Cambridge Isotope Laboratories)
N/A
HRMS rapid PCB screening calibration soln CS 0 1 unlabeled 13C12 99
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Image Search Results


The protein expression of MEF2C is regulated by m6A modification. (A,B) MEF2C and FTO protein levels after FTO knockdown and overexpression on the 4th day after differentiation. (C,D) MEF2C and METTL3 protein levels after METTL3 knockdown and overexpression for 4th day post differentiation. (E,F) Treatment with a global methylation inhibitor, 3-Deazaadenosine (DAA), for 24 and 48 h led to the downregulation of the MEF2C protein levels in bovine skeletal myoblasts. The results are presented as the means ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001, siNC vs. siRNA samples and DMSO vs. DAA at 24h; # p < 0.05, # # # p < 0.001, empty vector vs. overexpression plasmid samples and DMSO vs. DAA at 48h), using Student's t test.

Journal: Frontiers in Veterinary Science

Article Title: MEF2C Expression Is Regulated by the Post-transcriptional Activation of the METTL3-m 6 A-YTHDF1 Axis in Myoblast Differentiation

doi: 10.3389/fvets.2022.900924

Figure Lengend Snippet: The protein expression of MEF2C is regulated by m6A modification. (A,B) MEF2C and FTO protein levels after FTO knockdown and overexpression on the 4th day after differentiation. (C,D) MEF2C and METTL3 protein levels after METTL3 knockdown and overexpression for 4th day post differentiation. (E,F) Treatment with a global methylation inhibitor, 3-Deazaadenosine (DAA), for 24 and 48 h led to the downregulation of the MEF2C protein levels in bovine skeletal myoblasts. The results are presented as the means ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001, siNC vs. siRNA samples and DMSO vs. DAA at 24h; # p < 0.05, # # # p < 0.001, empty vector vs. overexpression plasmid samples and DMSO vs. DAA at 48h), using Student's t test.

Article Snippet: Additionally, MEF2C protein level was substantially decreased after 24 and 48 h of treatment with a global methylation inhibitor, 3-deazaadenosine (DAA) (4 μM, 86583-19-9, TargetMOI, MA, USA), without affecting its mRNA expression ( , ).

Techniques: Expressing, Modification, Knockdown, Over Expression, Methylation, Plasmid Preparation

MEF2C promotes the differentiation of bovine myoblasts by posttranscriptional activation of the METTL3-m 6 A-YTHDF1 axis. METTL3 catalyzes the N 6 -methylation of MEF2C mRNA, and YTHDF1 recognizes this modification site to promote the translation of MEF2C. Then, MEF2C can directly bind to the promoter region of METTL3 to activate its expression, suggesting that there is a positive feedback loop underlying the process of bovine skeletal myoblast differentiation.

Journal: Frontiers in Veterinary Science

Article Title: MEF2C Expression Is Regulated by the Post-transcriptional Activation of the METTL3-m 6 A-YTHDF1 Axis in Myoblast Differentiation

doi: 10.3389/fvets.2022.900924

Figure Lengend Snippet: MEF2C promotes the differentiation of bovine myoblasts by posttranscriptional activation of the METTL3-m 6 A-YTHDF1 axis. METTL3 catalyzes the N 6 -methylation of MEF2C mRNA, and YTHDF1 recognizes this modification site to promote the translation of MEF2C. Then, MEF2C can directly bind to the promoter region of METTL3 to activate its expression, suggesting that there is a positive feedback loop underlying the process of bovine skeletal myoblast differentiation.

Article Snippet: Additionally, MEF2C protein level was substantially decreased after 24 and 48 h of treatment with a global methylation inhibitor, 3-deazaadenosine (DAA) (4 μM, 86583-19-9, TargetMOI, MA, USA), without affecting its mRNA expression ( , ).

Techniques: Activation Assay, Methylation, Modification, Expressing